Alopecia Areata: An Immunologic Disease?

Alopecia areata: an update.

Alopecia areata (AA) is a common form of non-scarring hair loss of scalp and/or body. Genetic predisposition, autoimmunity, and environmental factors play a major role in the etiopathogenesis of AA. Patchy AA is the most common form. Atopy and autoimmune thyroiditis are most common associated conditions. Peribulbar and intrabulbar lymphocytic inflammatory infiltrate resembling "swarm of bees" i...

Alopecia areata.

n engl j med 367;3 nejm.org july 19, 2012 279 methacin should be used in addition to pancre­ atic stents in high­risk patients. However, post hoc analysis of our trial suggests that indometha­ cin may obviate the need for prophylactic pan­ creatic stent placement (unpublished data), and we therefore agree with Baron et al. that com­ parative effectiveness studies of indomethacin and pancreatic ...

Alopecia areata.

Alopecia areata is a frequent cause of hair loss. The origin of disease is not fully understood. However there are indications for a T-cell mediated autoimmune process. Genetic, immunologic and psychologic factors are important for the outbreak of disease. Most patients show localized patches of acute hair loss, where regrowth is observed spontaneously or with simple topical treatment within fe...

Alopecia Areata

Alopecia areata in patients with inflammatory bowel disease: an overview.

Alopecia areata (AA) is one of the most common causes of non-scarring hair loss, which is associated with the premature induction of hair follicle regression. The pathogenesis of AA is unknown, although it is believed that a complicated autoimmune mechanism with Th1 lymphocytes and proinfammatory cytokines, such as IFN-γ, TNF-α, IL-1 and IL-2, may be involved. AA may occur as a single disease e...